Allergen-Specific Tolerance Induction: Of Mice and Men

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Allergen-specific tolerance induction: of mice and men.

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Allergen-Specific Tolerance Induction: Of Mice and Men

gen tolerance. In this regard, animal models represent very helpful tools to analyze the immune effects of AIT in more detail since they allow investigators to focus on certain aspects when evaluating the immune mechanisms of tolerance induction, and can thus close a gap between in vitro analysis and immunological studies in humans [10] . A variety of mouse models have been developed to study t...

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Allergen-Specific Tolerance Induction: Of Mice and Men

gen tolerance. In this regard, animal models represent very helpful tools to analyze the immune effects of AIT in more detail since they allow investigators to focus on certain aspects when evaluating the immune mechanisms of tolerance induction, and can thus close a gap between in vitro analysis and immunological studies in humans [10] . A variety of mouse models have been developed to study t...

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Tolerance: of mice and men.

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Induction and regulation of allergen-specific IgE

The immune response is characterized by an initial rapid activation of the innate defence system, geared at recognizing common structures shared by many microorganisms. This innate immune response is a prerequisite to mount a highly antigenspecific adaptive immune response consisting of T-cell differentiation into effector subsets and B-cell differentiation into antibody-secreting plasma cells....

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ژورنال

عنوان ژورنال: International Archives of Allergy and Immunology

سال: 2015

ISSN: 1018-2438,1423-0097

DOI: 10.1159/000375406